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Sleep Was the First Thing to Change

Sleep can change before, during, or after depression or anxiety, and it can also have another cause entirely. This guide explains what the evidence supports, what else to check, and how patients and families can respond without turning one bad night into a verdict.

Originally published September 2, 2026

Last reviewed September 2, 2026

Clinical review: Fady Boules, PMHNP-BC

Sleep often changes before mood or anxiety does. That makes it a useful signal to notice and a poor basis for a diagnosis.

This is Part 5 of a five-part series on sleep and mental health. The other parts cover Less Time in Bed, More Consolidated Sleep, The Harder You Try, the Further It Gets, You’re Not Weak. It May Be Rebound, and He Can’t Fall Asleep. It May Not Be Defiance.

Maybe you noticed it before you had words for anything else. You began lying awake, waking too early, sleeping at odd hours, or needing new naps. Your partner saw it too. Does that mean depression or anxiety is returning?

Sometimes sleep is the first visible change. It can be a useful clue. It is not a diagnosis or a reliable forecast. Insomnia, depression, and anxiety can affect one another in both directions. A medicine change may also explain the change. So may a body-clock problem, breathing disorder, pain, stress, or substance. This article shows how to notice a pattern without turning one night into an emergency. Contact the treating clinician if the change lasts or affects daily life. Call sooner if it came before an earlier episode. Ask for sleep and mental health to be assessed together.

Key takeaways

  • A sleep change can come before, during, or after depression or anxiety. It can also have another cause.
  • Persistent insomnia deserves assessment and treatment in its own right. It is not always only a symptom.
  • CBT-I reliably helps insomnia. When depression is also present, it may improve depression outcomes, but it does not replace depression care.
  • Anxiety symptoms may improve when insomnia is treated. Evidence for remission of a diagnosed anxiety disorder is less certain.
  • Less sleep with unusual energy is different from being exhausted and unable to sleep. That difference can change how quickly help is needed.
Five things worth checking when sleep shifts, and the one pattern that should not wait. Tap the image to read it full size.

Think of sleep as a barometer, not a verdict

A barometer can show that the weather system is changing. It cannot tell you the whole cause. It cannot name the next storm or prove that danger is present.

Sleep can work the same way. A change from your usual pattern may invite a wider look. Check mood, worry, energy, medicines, substances, health, schedule, and safety. The analogy has a limit. Some episodes begin with no sleep warning. Most short sleep disruptions are not mental health episodes.

The title of this article is one person’s possible story. It is not a rule. For some people, sleep changes after mood or anxiety has already shifted. For others, sleep never becomes a useful warning sign.

What insomnia is, and what it is not

Insomnia means trouble falling asleep, staying asleep, or returning to sleep when enough time is available. It causes distress or affects the day. Chronic insomnia usually means that pattern occurs often for at least three months. A clinician usually identifies it through the person’s history and experience. One wearable score cannot do that. 17

Insomnia is not the same as having too little time for sleep. If work, school, caregiving, housing, or another demand leaves only five hours available, the main problem may be insufficient opportunity. Insomnia is also different from a body clock that runs later than the required schedule. Some people sleep well when allowed a later schedule but struggle to meet early work or school time.

Depression can include insomnia or early waking. It can also include long sleep or severe sleepiness. Anxiety can bring worry, panic, tension, nightmares, or nighttime alertness. Sleep alone cannot prove either diagnosis.

What bidirectional really means

Prospective studies follow people forward in time. A 2019 review compared groups with and without insomnia. The insomnia group had higher odds of later depression and anxiety. The estimated odds were about 2.8 times as high for depression. They were about 3.2 times as high for anxiety. Those numbers join results from different studies. They are not a personal risk calculator. 1

Studies also find the reverse pattern. Earlier depression or anxiety symptoms can predict later insomnia. This is why researchers use the word bidirectional, meaning that the timing can run both ways. 2

Earlier timing does not prove cause. Stress and genetics can affect both sleep and mental health. So can illness, trauma, medicines, substance use, schedule, or another sleep disorder. Self-report measures can also overlap. For example, many depression scales include a sleep question.

The practical point is simple: do not dismiss persistent insomnia as only depression or only anxiety. Also do not assume that fixing sleep will settle every part of a mood or anxiety disorder.

Who this evidence fits

The strongest treatment evidence comes from adults who had major depression and insomnia. A 2024 review included 19 randomized trials and 4,808 adults. Programs differed. Some involved a trained therapist. Some were digital. Many were added to antidepressant treatment, therapy, or usual care. 3

The anxiety evidence often comes from symptom scales. A general anxiety score is not the same as a confirmed diagnosis and remission interview. One trial included 120 adults with high insomnia and anxiety scores. It compared internet CBT-I with internet CBT for anxiety. Both groups improved. CBT-I was better for insomnia right after treatment. It worked about as well for anxiety symptoms. By three months, the programs did not differ. 7

Prevention evidence comes from narrower groups. One trial studied adults age 60 or older. Another studied youth age 15 to 25 in China who had insomnia disorder and subclinical depression. Their results should not be transferred automatically to every age, country, risk level, or treatment format.

Many trials excluded people with active mania or psychosis. They also excluded acute suicide risk, unstable substance use, or untreated sleep disorders. Studies of unipolar depression do not automatically fit bipolar depression. An adapted plan may be needed for shift work, pregnancy, postpartum care, or major illness. Unsafe daytime sleepiness also changes the plan.

What changed when insomnia was treated

Cognitive behavioral therapy for insomnia, or CBT-I, is a structured, multicomponent treatment. It is more than sleep tips. Article 1 in this series owns the full treatment explanation and its safety boundaries. This article focuses only on what happened to insomnia, depression, and anxiety when insomnia was treated as a separate target.

In the 2024 major-depression review, CBT-I increased the odds of insomnia remission and depression response compared with control conditions. At a typical eight-week time point, about 17% of people in control groups had a depression response. The review estimated about 32% with CBT-I, with a plausible range from 26% to 39%. Evidence certainty was rated moderate for that outcome. 3

That average is encouraging. It is not a promise. The control condition and treatment format varied. So did medicine use and support. Participants knew whether they received a behavioral treatment. Many outcomes came from their own reports. This can affect expectations. It does not make the outcomes meaningless. Insomnia is partly defined by lived sleep trouble and daytime effects.

One pivotal trial, called TRIAD, shows the limit. All 150 adults received an antidepressant plan. They also got seven CBT-I sessions or a credible insomnia control. CBT-I improved insomnia severity. Depression remission was 44% with CBT-I and 36% with the control. That difference was not statistically clear. Early sleep improvement was linked with later remission in one analysis. That link does not prove the mechanism. 4

Another trial compared CBT-I and escitalopram plans in 107 adults. Depression improved in every group. The groups did not differ clearly on depression. Lab sleep showed less wake time in the CBT-I groups. Sleep diaries did not show the same clear group difference. This is not a conflict to hide. A diary records sleep as the person lived it. A sleep study records sleep in a lab. Neither is the one true result. 5

A digital trial in older men also warns against assuming lasting gains. Sleep improved at first. By six months, the groups did not differ in insomnia or depression. Anxiety did not differ at any measured time. A useful treatment may still need support, a good fit, and relapse planning. 6

Harms and dropout were not tracked in the same way across trials. The 2024 review found an unclear dropout difference. The youth prevention trial reported no treatment-related adverse events. Neither finding proves that every format fits every person. Report unsafe sleepiness, marked mood activation, or a plan that feels too hard.

Depression and anxiety are not the same evidence lane

Adults with major depression and insomnia can treat both at the same time. CBT-I reliably improves insomnia. It may also raise the chance of a depression response. Some analyses removed sleep items from depression scores and still found a benefit. This suggests the result is not only a better sleep item. Yet no trial shows that every symptom will improve. The same is true for relationships, work, and quality of life. 8

For anxiety, the safest answer is narrower. Insomnia treatment may reduce general anxiety symptoms. We know less about remission or prevention of a diagnosed anxiety disorder. Panic, PTSD, obsessive-compulsive disorder, and other conditions may still need their own care.

A broader review of sleep interventions found average improvements in depression and anxiety. It mixed many treatments and populations, so it cannot show that CBT-I alone treats a diagnosed mental disorder. 9

An intervention tested as an add-on should be described as an add-on. If the study kept antidepressants or psychotherapy in place, it cannot show that CBT-I works as a stand-alone replacement.

Can treating insomnia prevent depression?

Possibly for some defined groups, but the results are not universal.

One trial studied 291 adults age 60 or older. They had insomnia but no current major depression. It compared group CBT-I with active sleep education. Over 36 months, major depression occurred or returned in 12.2% of the CBT-I group. The rate was 25.9% in the education group. 10

Another trial studied 708 Chinese youth age 15 to 25. They had insomnia disorder and mild depression symptoms. A six-week CBT-I app was compared with a health education app. At 12 months, major depression had developed in 10% of the CBT-I group. The rate was 18% in the control group. 11

A larger digital trial of 1,149 adults found a different pattern. Depression scores improved. New major depression diagnoses did not differ in a clear way. Only 44% completed the six-month check. That adds doubt. 12

The evidence supports research and carefully selected prevention programs. It does not support the headline that CBT-I prevents depression for everyone. Evidence for preventing anxiety disorders is even less established.

A sleep change can be a personal clue

Group averages are not the only useful information. Your own repeated pattern can matter. Maybe insomnia appeared before two earlier depression episodes. That history may belong in a shared relapse plan.

Use the pattern as a prompt, not a verdict. Look for change across several nights. Also note daytime function and other symptoms. Ask what else changed. Consider illness, stress, travel, work, pain, caffeine, alcohol, cannabis, nicotine, or medicine.

Do not wait for several nights when danger is already clear. Suicidal intent, inability to stay safe, psychosis, dangerous behavior, severe breathing trouble, overdose, or another emergency needs immediate help.

Tired or wired?

Being exhausted but unable to sleep is common in insomnia. Sleeping much less without the expected tiredness is a different clue.

Seek prompt assessment when much less sleep comes with high or irritable energy. Other clues include fast speech, racing thoughts, more activity, unusual confidence, risky choices, agitation, or psychotic symptoms. This pattern can occur in mania or hypomania. It can also occur in a mixed mood state, after medicine activation, with stimulant use, or for another reason.

Reduced need for sleep by itself does not diagnose bipolar disorder. Bipolar depression can include insomnia and exhaustion. The purpose of this question is to route care, not to let relatives make a diagnosis. 19 For a fuller plan, see NPFADY’s reduced-need-for-sleep and bipolar warning-sign guide, Retrofit in Calm Weather.

Check for other explanations

A new sleep change deserves a wide lens. Snoring, gasping, and breathing pauses can point to sleep apnea. An urge to move the legs can point to restless legs syndrome. Nightmares or nighttime panic may need trauma or anxiety care. Severe sleepiness needs a different check from insomnia. So do sudden sleep attacks.

Pain, reflux, nighttime urination, menopause symptoms, pregnancy, thyroid illness, and other medical problems can disturb sleep. Caffeine, alcohol, cannabis, nicotine, stimulants, steroids, decongestants, and sedating products can change timing, depth, or next-day alertness.

A start, stop, dose change, or missed dose can also matter. Do not change a prescription based on this article. Article 2 owns rebound, withdrawal, and clinician-guided discontinuation.

Essential ingredients

Must keepDetail
Assess sleep and mental health together. Ask about sleep time, energy, safety, medicines, substances, and other sleep signs. Keep needed mental-health care. Use properly delivered CBT-I when it fits.May adapt: Change how the short baseline is recorded. Invite a trusted person only if wanted. Consider digital, group, video, or individual care when the evidence and fit support it.
Avoid: Do not diagnose from one night or one tracker score. Do not start a sleep-window plan alone. Do not replace mental-health care with sleep tips. Do not change medicine without the prescriber. Avoid family surveillance.

What to do this week

Choose one target: a clear change from your usual sleep and daytime function. For three to seven days, note sleep timing in broad terms. Mark whether you felt tired or unusually energized. Add one daytime effect. Note any recent change in medicine, substance, illness, stress, or schedule.

Then take no more than three steps:

  1. Share the pattern with the clinician who treats your mood, anxiety, or sleep.
  2. Ask whether insomnia should be assessed and treated as a separate target.
  3. Agree on one review point and one urgent-call threshold.

You need a few minutes and a private note. Include only the people you want. On a hard day, use one sentence: “My sleep changed for several nights, and my daytime energy or function changed too.” If tracking feeds worry, stop collecting detail. Bring that sentence instead. A missed day needs no catch-up. At review, continue, simplify, adapt, or get more help.

Action and troubleshooting asset

What the reader seesDetail
One poor night after stressPossible explanation: Normal short-term variation or acute stress
Reasonable next step: Return to the usual plan and avoid treating the night as a forecast
When reassessment is needed: If the pattern persists, function drops, or other symptoms appear
Several nights of insomnia with tirednessPossible explanation: Insomnia, mood, anxiety, pain, schedule, medicine, substance, or another sleep disorder
Reasonable next step: Record a short pattern. Contact the clinician.
When reassessment is needed: Call sooner for unsafe sleepiness, driving risk, severe decline, or breathing signs.
Less sleep with unusual energy or behaviorPossible explanation: Possible activation, mania, hypomania, mixed symptoms, medicine effect, or substance effect
Reasonable next step: Seek prompt assessment. Arrange help with safety.
When reassessment is needed: Use emergency care for psychosis, dangerous behavior, or inability to stay safe.
Sleep improves but mood does notPossible explanation: Insomnia may be responding. Depression or anxiety may still need care.
Reasonable next step: Keep mental-health review in place.
When reassessment is needed: Call promptly for worse depression or suicidal thoughts.
A tracker and your experience disagreePossible explanation: Device limits, sleep-state difference, or night variation
Reasonable next step: Use symptoms and function. Discuss data only if it helps care.
When reassessment is needed: Reassess if monitoring raises distress or delays care.

Your job and your family’s job

Your jobDetail
Report change honestly. Describe tiredness, energy, function, medicines, and substances. Seek care for sleep and mental health. Do not drive when sleepy.Your family’s job: With your consent, notice change from your baseline. Ask calm questions. Help contact care. Act on clear safety concerns.
What neither of you has to do: Neither person must predict an episode or make a diagnosis. Do not audit a wearable, enforce sleep, hide medicine, or manage a crisis alone.
When professional help is needed: Get help for persistent insomnia, loss of function, a prior-episode pattern, possible mania, medicine concerns, breathing signs, unsafe sleepiness, suicidal thoughts, psychosis, or immediate danger.

Family involvement is optional and revocable except when immediate safety requires action. Agree on what may be observed, what may be shared, and when the plan ends. Kind support is not the same as nightly checking.

Do not drive when sleepy. Arrange another ride. 21

Words you can use

Patient: “My sleep has changed from my usual pattern for several nights. I am tired, and my concentration is worse. Can we assess sleep and mood together?”

Family member: “I noticed your sleep changed. Are you tired and unable to sleep, or are you sleeping less without feeling tired?”

Clinician: “I want to keep my mental-health treatment in place and ask whether CBT-I fits. What other sleep or medical causes should we check first?”

When safety is a concern, ask plainly: “Are you thinking about suicide?” Asking does not plant the idea. Listen, stay present, and connect the person with help. Do not promise secrecy about immediate danger. 18

Measure progress in real life

Do not grade treatment from one night or one score. Review several outcomes. Is there less wakefulness or distress? Is daytime alertness steadier? Check driving, work, focus, mood, anxiety, missed duties, family conflict, and treatment burden.

Sleep may improve before mood, after mood, or on a different path. No progress does not prove poor effort. The diagnosis or plan may need review. The care format, support, or another disorder may also matter.

Access at three levels

Start today: Write the one-sentence baseline. List current prescriptions and store-bought products. Add caffeine, alcohol, cannabis, nicotine, and other substances that change sleep. Do not change them on your own.

Lower-cost support: Ask a primary-care clinic or health system about lower-cost CBT-I. A community mental-health center, insurer, employer program, or training clinic may also know local choices. Ask about groups, video visits, brief care, or guided digital care. Check age limits, state coverage, privacy, support, cost, and language access. Ask what happens if mood or safety worsens before care starts.

Formal care: Look for a sleep clinician or another clinician trained in CBT-I. That person should work with the prescriber or therapist who treats mental health. Ask what parts of CBT-I are included. Ask how safety and possible bipolar signs are checked. Ask how progress and care teamwork will work. Housing, disability, shift work, caregiving, cost, transport, and internet access affect treatment fit. They are not personal failures.

A simple coordination plan

Write down the goal, short baseline, plan, owners, timing, and review date. Add what family may know or share. Name the signs that trigger a call. Give each clinician only the facts needed for the plan. A portal message may not reach an urgent team in real time.

Frequently asked questions

Does insomnia mean I am becoming depressed?

No. Insomnia is linked with higher later depression risk in groups. It cannot diagnose or predict depression for one person. Look at duration, daytime effect, mood, interest, energy, function, medicines, substances, and other sleep causes. A repeated personal pattern can guide a call to your clinician.

Can CBT-I treat depression too?

CBT-I reliably treats insomnia. Pooled trials found better depression response on average when major depression and insomnia occurred together. Some trials did not find a clear remission benefit. CBT-I should support, not replace, needed depression care.

What about anxiety?

Anxiety symptoms may improve when insomnia is treated. We know less about remission or prevention of a diagnosed anxiety disorder. Keep care for that disorder in place. This is vital for panic, PTSD, obsessive-compulsive disorder, or severe anxiety.

How can my family notice change without watching me every night?

While things are stable, agree on one or two signs. Choose one calm check-in and one call point. Use change from your baseline, not a wearable score. You can revise or end routine checks. Immediate danger is the exception. Safety comes first.

Does better sleep lower suicide risk?

Sleep treatment may help within broader care. CBT-I has not been shown to prevent suicide attempts or deaths. Sleep trouble is linked with suicidal outcomes. It is a weak stand-alone predictor. Suicidal thoughts need direct assessment and support. That is true even when sleep looks normal or is improving. 13 14 15 16

When to get help

LevelWhat to do
Emergency help nowCall 911 or go to the nearest emergency department for immediate danger. Do the same for inability to stay safe, an attempt in progress, dangerous psychosis or mania, seizure, suspected overdose, severe breathing trouble, or inability to awaken. In the United States, call or text 988 for suicide or mental-health crisis support.
Prompt clinical evaluationContact a clinician promptly for suicidal thoughts without immediate danger. Also call for much less sleep with unusual energy, hallucinations, fast decline in mood, unsafe sleepiness, a driving near-miss, breathing pauses, substance concern, or a new medicine problem. Do not drive when sleepy.
Routine troubleshootingSet a review when goals are unclear or the plan is too hard. Review blocked access, symptoms that last, or sleep that improves while mental health does not. No progress after a fair trial also needs review. The answer may be a change, another diagnosis, or more care. It is not more pressure.

If you or someone else may be in immediate danger, call 911. For suicide or mental-health crisis support in the United States, call or text 988 or use 988 chat. 20

This article is for education and is not a diagnosis or an individual treatment plan. Sleep problems can have more than one cause. A qualified clinician can help you choose care that fits your health, medicines, schedule, and safety needs. Do not start, stop, taper, or change a prescription medicine based on this article.

Tools you can use

These tools are optional. They are not diagnostic scales, a crisis plan, or a treatment prescription. Use the minimum detail needed. Stop routine tracking if it increases fear, conflict, or surveillance.

A. Personal-baseline sleep-change tracker

Consent and purpose

  • I am using this for: ____________________________________________
  • I want support from: ___________________________________________
  • They may see or share: _________________________________________
  • Review or stop date: ___________________________________________
Date or short periodDetail
****
****
****
****
****

Review, not a score

  • Is the change brief, persistent, or recurring?
  • Is function or safety changing?
  • Am I tired and unable to sleep, or sleeping less without expected tiredness?
  • Does this match a prior personal pattern?
  • Continue, simplify, stop tracking, or contact care: __________________

B. Observe, Ask, Act card

Observe, with consent when possible

  • Look for change from the person’s own baseline across several nights, not one isolated night.
  • Notice trouble falling asleep, repeated waking, early waking, altered timing, new naps, or long sleep.
  • Notice tiredness and distress versus unusual energy despite less sleep.
  • Notice withdrawal, loss of interest, worry, irritability, concentration change, or reduced function.
  • Note recent illness, stress, medicine change, or substance use.

Ask calmly

  • “I noticed your sleep changed. Are you tired and unable to sleep, or sleeping less without feeling tired?”
  • “How have your mood and anxiety been?”
  • “Would you like help contacting your clinician?”
  • When concerned: “Are you thinking about suicide?”

Act

  • Contact the treating clinician for a persistent or recurring pattern, meaningful impairment, or a change that has accompanied an earlier episode.
  • Seek prompt assessment for much less sleep with increased energy, agitation, fast speech, unusual behavior, risky choices, or psychosis.
  • Use 988 for suicide or mental-health crisis support in the United States. Use 911 or emergency services for immediate danger or inability to stay safe.

Boundary: Family members are observers and supporters, not diagnosticians, tracker auditors, enforcers, or sole safety managers.

C. Care-coordination sheet

FieldShared plan
Goal in daily life
Short baseline and time period
Insomnia strategy and provider
Mood or anxiety strategy and provider
Current medicines and substances reviewed by
Patient-owned step
Family step, if consented
Frequency and review date
Information that may be shared
Prompt call threshold
Emergency route
Barrier and adaptation

D. Extended script bank

Starting the conversation with a clinician

“Sleep may be part of my mood pattern, but I do not want to assume the cause. Can we check insomnia, other sleep disorders, medicines, and mental health together?”

“My sleep improved, but my mood did not. What should we continue, and what needs a separate treatment change?”

“I am interested in CBT-I. Does this option include the full treatment, who monitors it, and how will it fit with my current care?”

Setting a family boundary

“Please ask once about how I am functioning, not for my sleep score every morning.”

“You may help me call the clinic if this pattern lasts until our agreed review point. Please do not read my tracker unless I ask.”

“If I seem unusually energized while sleeping very little, tell me what you notice and help me contact care. Do not argue about a diagnosis.”

Family support

“I am not trying to diagnose you. I noticed a change from your usual pattern and want to know what support would help.”

“We do not have to solve this tonight. Should I help write one message to your clinician?”

“You seem too sleepy to drive. I will help arrange another ride.”

E. Differential routing mini-sheet

ClueDetail
Not enough hours availableAsk about: Work, school, caregiving, housing
Route: Protect opportunity and address barriers
Better sleep on a later scheduleAsk about: Body clock, shift work, accumulated sleep debt
Route: Sleep or circadian evaluation when impairing
Snoring or gaspingAsk about: Breathing pauses, morning headache, sleepiness
Route: Sleep evaluation
Urge to move legsAsk about: Timing, relief with movement, iron or medicine factors
Route: Primary care or sleep evaluation
Nightmares or panicAsk about: Trauma, nocturnal panic, safety
Route: Mental-health and sleep evaluation
Medicine or substance changeAsk about: Start, stop, missed dose, timing, interaction
Route: Prescriber or pharmacist; no self-directed change
Much less sleep and unusual energyAsk about: Speech, thoughts, activity, behavior, psychosis
Route: Prompt or emergency assessment based on safety

References

1. Hertenstein E, Feige B, Gmeiner T, et al. Insomnia as a predictor of mental disorders: A systematic review and meta-analysis. Sleep Medicine Reviews. 2019;43:96-105. doi:10.1016/j.smrv.2018.10.006. PMID 30537570. 2. Alvaro PK, Roberts RM, Harris JK. A systematic review assessing bidirectionality between sleep disturbances, anxiety, and depression. Sleep. 2013;36(7):1059-1068. doi:10.5665/sleep.2810. PMID 23814343. 3. Furukawa Y, Nagaoka D, Sato S, et al. Cognitive behavioral therapy for insomnia to treat major depressive disorder with comorbid insomnia: A systematic review and meta-analysis. Journal of Affective Disorders. 2024;367:359-366. doi:10.1016/j.jad.2024.09.017. PMID 39242039. 4. Manber R, Buysse DJ, Edinger J, et al. Efficacy of Cognitive-Behavioral Therapy for Insomnia Combined With Antidepressant Pharmacotherapy in Patients With Comorbid Depression and Insomnia: A Randomized Controlled Trial. Journal of Clinical Psychiatry. 2016;77(10):e1316-e1323. doi:10.4088/JCP.15m10244. PMID 27788313. 5. Carney CE, Edinger JD, Kuchibhatla M, et al. Cognitive Behavioral Insomnia Therapy for Those With Insomnia and Depression: A Randomized Controlled Clinical Trial. Sleep. 2017;40(4):zsx019. doi:10.1093/sleep/zsx019. PMID 28199710. PMCID PMC5806549. 6. Glozier N, Christensen H, Griffiths KM, et al. Adjunctive Internet-delivered cognitive behavioural therapy for insomnia in men with depression: A randomised controlled trial. Australian & New Zealand Journal of Psychiatry. 2019;53(4):350-360. doi:10.1177/0004867418797432. PMID 30191722. 7. Mason EC, et al. Co-occurring insomnia and anxiety: a randomized controlled trial of internet cognitive behavioral therapy for insomnia versus internet cognitive behavioral therapy for anxiety. Sleep. 2023;46(2):zsac205. doi:10.1093/sleep/zsac205. PMID 36041459. 8. Hertenstein E, Trinca E, Wunderlin M, et al. Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: A systematic review and meta-analysis. Sleep Medicine Reviews. 2022;62:101597. doi:10.1016/j.smrv.2022.101597. PMID 35240417. 9. Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Medicine Reviews. 2021;60:101556. doi:10.1016/j.smrv.2021.101556. PMID 34607184. PMCID PMC8651630. 10. Irwin MR, Carrillo C, Sadeghi N, Bjurstrom MF, Breen EC, Olmstead R. Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia: A Randomized Clinical Trial. JAMA Psychiatry. 2022;79(1):33-41. doi:10.1001/jamapsychiatry.2021.3422. PMID 34817561. PMCID PMC8733847. 11. Chen SJ, Que JY, Chan NY, et al. Effectiveness of app-based cognitive behavioral therapy for insomnia on preventing major depressive disorder in youth with insomnia and subclinical depression: A randomized clinical trial. PLOS Medicine. 2025;22(1):e1004510. doi:10.1371/journal.pmed.1004510. PMID 39836656. PMCID PMC11750088. 12. Christensen H, Batterham PJ, Gosling JA, et al. Effectiveness of an online insomnia program on depression: a randomised controlled trial. The Lancet Psychiatry. 2016;3(4):333-341. doi:10.1016/S2215-0366(15)00536-2. PMID 26827250. Correction: PMID 27063380. 13. Liu RT, Steele SJ, Hamilton JL, et al. Sleep and suicide: A systematic review and meta-analysis of longitudinal studies. Clinical Psychology Review. 2020;81:101895. doi:10.1016/j.cpr.2020.101895. PMID 32801085. PMCID PMC7731893. 14. Pigeon WR, Funderburk J, Cross W, Bishop TM, Crean HF. Brief CBT for Insomnia delivered in primary care to patients endorsing suicidal ideation: A proof-of-concept randomized clinical trial. Translational Behavioral Medicine. 2019;9(6):1169-1177. doi:10.1093/tbm/ibz108. PMID 31271210. 15. Nazem S, Sun S, Barnes SM, et al. Impact of an internet-based insomnia intervention on suicidal ideation and associated correlates in veterans at elevated suicide risk. Translational Behavioral Medicine. 2024;14(11):673-683. doi:10.1093/tbm/ibae032. PMID 38864695. PMCID PMC11568844. 16. Pigeon WR, Funderburk JS, Bishop TM, Cross W, Crean HF. Brief Cognitive Behavioral Insomnia Treatment for Primary Care Veterans at Elevated Risk for Suicide: A Randomized Clinical Trial. Psychotherapy and Psychosomatics. Published online February 12, 2026:1-13. doi:10.1159/000550973. PMID 41678426. 17. Edinger JD, Arnedt JT, Bertisch SM, et al. Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2021;17(2):255-262. doi:10.5664/jcsm.8986. PMID 33164742. 18. National Institute of Mental Health. Frequently Asked Questions About Suicide. Accessed August 31, 2026. Official NIMH page. 19. National Institute of Mental Health. Bipolar Disorder. Accessed August 31, 2026. Official NIMH page. 20. Substance Abuse and Mental Health Services Administration. 988 Frequently Asked Questions. Updated December 16, 2025. Accessed August 31, 2026. Official SAMHSA page. 21. National Highway Traffic Safety Administration. Drowsy Driving: Avoid Falling Asleep Behind the Wheel. Accessed August 31, 2026. Official NHTSA page.

If you or someone you know is in crisis

  • Call 911 or go to your nearest emergency room for any life-threatening emergency.
  • 988 Suicide & Crisis Lifeline — call or text 988, available 24/7. En español: marque 988 y oprima 2. Veterans: 988 and press 1, or text 838255.
  • Crisis Text Line — text HOME to 741741.
  • The Trevor Project (crisis support for LGBTQ+ young people) — call 1-866-488-7386, or text START to 678-678.
  • National Sexual Assault Hotline (RAINN) — call 1-800-656-HOPE (4673) or text HOPE to 64673; free, confidential, 24/7. Online chat at RAINN.org/hotline.
  • National Domestic Violence Hotline — call 1-800-799-SAFE (7233) or text START to 88788; 24/7, help in 200+ languages. Online chat at TheHotline.org. If your phone or computer may be monitored, calling from a safer device is an option.
  • Riverside CountyInland SoCal Crisis Helpline 951-686-HELP (4357), 24/7 (Inland SoCal United Way / 211+, in partnership with RUHS-BH); Community Access, Referral, Evaluation and Support (CARES) Line 800-499-3008, 24/7.
  • San Bernardino CountyAccess Unit (Behavioral Health Helpline) 888-743-1478, 24/7; Mobile Crisis/CCRT 800-398-0018 (24/7, all ages) or text 909-420-0560. Arrowhead Regional Medical Center (ARMC) has a dedicated walk-in adolescent psychiatric ER (ages 13–17).
  • Children under 13 — call 911 for immediate danger, contact your county's mobile crisis team (they respond to all ages), or go to the nearest pediatric emergency room.
  • California Peer-Run Warm Line (non-crisis — someone to talk to) — call or text 1-855-600-WARM (9276); daytime and evening hours, not a 24/7 line.
  • NP Fady (non-emergency) — for routine scheduling or questions, call (909) 707-6261. This line is not monitored for emergencies.