Skip to content

Depression

Behind the Closed Door: Depression and Anxiety in Teens Ages 13–18

Privacy is normal at 13–18. Disappearing is not. How teen depression and anxiety really look, what gets hidden, and exactly when and how to step in.

Originally published August 6, 2026

Last reviewed August 6, 2026

Clinical review: Fady Boules, PMHNP-BC

Teenagers are supposed to pull away, sleep late, guard their privacy, and roll their eyes. Most of that is healthy. Here is how to tell ordinary adolescence from depression and anxiety, the versions teens hide best, and what to do — including on the worst day.

Part 3 of a three-part series. Also see: ages 5–8 and ages 9–12.

The teen years are when depression and anxiety become common. In 2025, about 15% of U.S. adolescents ages 12–17 — 3.7 million teens — had a major depressive episode; only about 58% of them got any mental health treatment. [1] In the latest national school survey, about 4 in 10 high schoolers reported persistent sadness or hopelessness — a symptom report, not a diagnosis, but striking. [2] By 18, roughly 1 in 3 adolescents has met criteria for an anxiety disorder at some point. [3] Both are treatable, and most teens who get care improve. The parent job: spot real signals inside normal turbulence, then act early and calmly.

If you’re worried right now

Get emergency help now — call 911 or go to the nearest emergency room — if your teen:

  • Has attempted suicide or self-harmed in a way needing medical care
  • Talks about suicide and has a plan, has researched methods, or has access to means
  • Has taken pills or another substance in a concerning way
  • Is severely agitated, violent, unsafe while intoxicated, or detached from reality
  • Cannot be kept safe at home right now

Free, 24/7 crisis support:

  • Call or text 988
  • Chat at 988lifeline.org
  • Text HOME to 741741 (Crisis Text Line)
  • LGBTQ+ young people: The Trevor Project, 1-866-488-7386, or text START to 678-678

Get same-day professional advice — clinician today, or 988 for guidance — if your teen:

  • Mentions wanting to die, being a burden, or “everyone would be better off,” even jokingly
  • Shows new or escalating self-harm
  • Is giving away valued possessions or sending goodbye-flavored messages
  • Shows sudden, unexplained calm after deep despair
  • Has stopped eating, sleeping, or functioning almost entirely

Make an appointment and start tracking if:

  • The patterns in this article persist two weeks or more, keep returning, or are eroding school, friendships, sleep, or self-care

Worst-day facts: asking directly about suicide does not increase risk [4] — and locking or removing firearms and securing medications measurably lowers it. [5][6]

What depression can look like at 13–18

  • Irritability as loudly as sadness. An angry, prickly teen may be a depressed teen. Irritable mood formally counts toward the diagnosis in adolescents. [7][8]
  • Numbness and lost pleasure. Quitting the sport or instrument they loved. “I don’t care” as a default. Ask how they feel and you’ll often hear “nothing.”
  • Burden and worthlessness talk. “I ruin everything.” “You’d be fine without me.” Never filler — burden talk is a recognized warning sign for suicide risk. [9][10]
  • Sleep turned inside out. Teens naturally shift later — that’s biology. [11] Depression differs: awake for hours, 4 a.m. waking, or 12+ hours never feeling rested, with days falling apart. [12]
  • Self-care decline. Showers skipped, appearance abandoned; appetite or weight changes, fatigue, slowed movement or agitation.
  • Withdrawal with a screen glow. Isolated in the room yet “online with friends” — heavy online activity can coexist with deep loneliness.

What anxiety can look like at 13–18

  • Social anxiety comes of age. Fear of judgment far beyond shyness: skipping presentations, eating alone rather than risk the cafeteria. About 9% of teens meet criteria at some point. [3]
  • Panic attacks. Sudden surges — pounding heart, choking feeling, dizziness, terror of dying or losing control — peaking within minutes. Panic disorder typically emerges in adolescence. First episodes deserve a medical check; after that, the trap is avoidance — dropping the class, the mall, the car, the school. [13]
  • The worry engine. Grades, college, money, health. Generalized anxiety often looks like a capable student quietly grinding down: headaches, stomach trouble, tension, poor sleep. School slides — or grim overachievement suddenly collapses.
  • Perfectionism and procrastination. Both can be anxiety: one fights fear by overworking, the other by never starting.
  • Reassurance and checking. Repeated “is this okay?” texts and constant checking. When rituals or intrusive thoughts dominate, consider OCD — a distinct condition.
  • School absenteeism. Mounting missed days with a vague medical story often has anxiety or depression underneath. It is a behavior with causes, not a diagnosis. [14]
  • Health and body worries. When food rules, weight terror, or compulsive exercise appear, think eating disorder and act early — these are medically serious.

The versions parents miss

  • The high-functioning teen. Honor roll, varsity, funny — and quietly hopeless. Parents’ and teens’ reports of inner distress agree only weakly across hundreds of studies. Grades and smiles are not proof of wellness. [15]
  • The “attitude problem.” Anger, defiance, risky driving, fights — externalizing behavior can coexist with real distress. Look underneath rather than just punishing the surface. [7]
  • The substance shortcut. Vaping, alcohol, and especially cannabis can be self-medication, cause, and complication at once. Adolescent cannabis use is linked to roughly 1.4-fold odds of later depression and 1.5-fold suicidal thinking — association, not proven causation, but reason to take seriously. [16]
  • Teens facing extra headwinds. Two-thirds of LGBQ+ high schoolers reported persistent sadness or hopelessness; 36% of LGBTQ+ young people seriously considered suicide in the past year. Identity is not the illness — rejection and stigma drive the risk, and family acceptance strongly protects. A parent’s response is real medicine. [2][17][18][19]
  • Teens adults misread. Suicide attempts have risen among Black adolescents, and Black youth remain less likely to receive treatment — distress too often read as a discipline problem. Culture shapes expression too — in some families pain speaks through the body, anger, or silence. [20][21] And boys report less sadness but die by suicide more often; their depression often wears anger. [2][9]

Two composite examples

Fictional composites — not real teens, and not diagnoses.

Emma, 17, keeps her grades up and makes everyone laugh. She also quit orchestra “to focus,” sleeps most of the weekend, and eats alone in her room. Last month she said, “You guys would be fine without me,” and laughed it off. Every adult would call her thriving. The quit activity, the heavy sleep, the isolation, and especially the burden comment say: ask directly, today.

Tyler, 14, went from B’s to failing, got caught vaping twice, and detonates over small requests. His friend group dissolved over the summer. His parents see defiance; the school sees a discipline case — yet anger and rule-breaking are sometimes the most visible layer of a depressed young teen. The question that changes the conversation: “What’s it actually been like for you lately?”

Rare but serious presentations

  • Psychosis: hearing or seeing things, bizarre beliefs, disorganized speech, steep decline — uncommon, always urgent.
  • Mania or mixed states: days of little sleep with unusual energy, pressured speech, grandiose plans, reckless behavior — sometimes mixed with despair. This changes both diagnosis and treatment. [7]
  • Catatonia: barely moving or speaking, odd postures, or agitated purposeless movement — rare, treatable, a medical urgency. [22]

What to watch: a parent observation table

Dormancy and dying look identical from the sidewalk — the buds are what tell them apart. Tap the image to read it full size.
AreaOrdinary adolescenceWorth attentionSame-day action
MoodMoody hours, eye-rollsIrritable or flat most days, 2+ weeksHopeless or burden talk
InterestsSwapping hobbiesQuitting everything, joy gone
SleepLate nights, weekend sleep-insInsomnia, 4 a.m. waking, 12+ hr daysDays with almost no sleep
SchoolOccasional slumpSliding grades, mounting absencesSudden refusal or collapse
FriendsNew circles, more privacyIsolation from everyone
Body & self-careLong showers, messy roomHygiene decline, weight shifts, constant achesNot eating or drinking
Digital lifeHeavy but social use3 a.m. use, account purges, dark postsGoodbye messages
SubstancesAny regular use, especially cannabis/nicotineIntoxication plus despair
SafetySelf-harm marks, reckless risk-takingDeath talk, plan, means-seeking, giving things away, sudden calm

A phase, a stress response, or something more?

Adolescence is not a disorder. Privacy, sleeping in, new music, pushing against rules — all expected. Use the clinician’s filter:

  1. Change from this teen’s baseline — the strongest single signal.
  2. Persistence. Bad days scatter; episodes settle in for weeks.
  3. Pervasiveness. Trouble in one arena reads differently from trouble everywhere.
  4. Proportion. A breakup earns real grief. Watch whether it lifts over weeks or deepens into worthlessness.
  5. Distress. Some teens will tell you they feel awful. Believe them the first time.
  6. Impairment. Grades, attendance, friendships, sleep, hygiene — count the costs.
  7. Narrowing. Avoidance that spreads: classes, then crowds, then the car, then the house.
  8. Safety signs. Never assigned a waiting period.

Paired examples: sleeping until noon Saturday is teen biology; lying awake until 3 a.m. nightly and failing first period is a symptom. [11][12] Wanting the door closed is privacy; dropping every friend and eating every meal alone is withdrawal. Fighting about curfew is development; “nothing matters anyway” is a flag.

And 13 is not 18. Young teens show more irritability and physical complaints and depend more on your observation; older teens show the classic adult picture, hide it better, and hold more autonomy — at 18 they generally control their own health information, so build collaboration habits now. [23]

When depression and anxiety travel together

Combined pictures are common: the anxious achiever sliding into hopelessness, the depressed teen housebound by panic. Depressed youth carry roughly eight-fold odds of an anxiety disorder, and 25–50% have both. [24][25] Anxiety usually arrives first and, untreated, raises later depression risk. [26] Combined presentations mean more impairment and risk — both belong in the plan, named and tracked.

Other things that can look similar

  • Medical causes and sleep debt: thyroid disease, anemia, mononucleosis and post-viral fatigue, sleep apnea, chronic pain — and plain sleep deprivation, which mimics and feeds depression. [11][12] Testing follows the story; no routine panel or scan diagnoses these conditions.
  • Substances and medications: cannabis, alcohol, nicotine, stimulant misuse, energy drinks; prescribed medicines including steroids and montelukast (boxed warning for mood and behavior changes). Isotretinoin (for acne) carries a label warning for mood changes, though controlled studies show no clear average rise in depression — report mood changes to the prescriber either way. [16][27][28]
  • Other psychiatric conditions: bipolar-spectrum illness, OCD, PTSD and trauma-related conditions, eating disorders, ADHD.
  • Environmental reality: bullying, discrimination, an unsafe home, academic mismatch, financial stress — real problems need fixing, not just coping skills.
  • More than one at once is the adolescent rule. [24]

What you can say and do

  • Open with observation, not indictment — in low-pressure moments. Cars, walks, late-night kitchens. “You’ve seemed exhausted and down for weeks. I’m not mad — I’m worried, and on your side.”
  • Ask the direct question when signs are there. “Are you having thoughts of killing yourself?” Plain words, calm voice. It does not increase risk. [4]
  • If the answer is yes: stay calm, thank them for telling you, and stay close if danger seems near. Secure medications and firearms. Call 988 or your clinician the same day; if danger is immediate, 911 or the ER. Skip the “promise me” contract — safety comes from assessment, a written safety plan, and means security, which cut repeat suicidal behavior nearly in half in a large ED study. [29][30]
  • Don’t promise total secrecy. “What you tell me stays between us unless your safety is at stake” is a promise you can keep.
  • Keep connection alive through the conflict. Eat together, drive them places, watch their show — warmth is the scaffolding recovery gets built on, and family acceptance measurably protects LGBTQ+ teens. [19]
  • Involve them in the plan. Teens who help choose the clinician, format, and goals engage better — help arranged with a teen beats help imposed on one.

How an evaluation usually works at this age

Expect the clinician to see your teen alone for part of the visit — standard practice, because teens disclose more privately. [15][31] Confidentiality gets explained, with its limits: safety concerns are always shared. Routine checkups now include annual depression and suicide-risk screening from age 12 and anxiety screening through 18; common tools: the PHQ-A, the SCARED, and the ASQ suicide-risk questions. [31][32][33][34][35] A full evaluation adds your history, school input, a physical exam with targeted labs if needed, and substance screening. A screen is a signal, never a verdict. A normal screen with a worried parent still deserves a closer look.

What helps: treatment at ages 13–18

  • Psychotherapy with real evidence: CBT for depression and anxiety, exposure-based work for panic and avoidance, and interpersonal therapy for adolescents (IPT-A), built around relationship stress. CBT and IPT carry the strongest evidence for teen depression; for anxiety, CBT roughly triples remission. [36][37][38]
  • For moderate-to-severe depression, combining treatments beats either alone. In the landmark TADS trial, 71% of teens improved by 12 weeks with fluoxetine plus CBT, versus 61% fluoxetine, 43% CBT, and 35% placebo. [39] If a first medication fails, switching plus CBT improved response in resistant teens (55% vs 41%). [40]
  • Medication facts, plainly. Fluoxetine (age 8+) and escitalopram (age 12+) are FDA-approved for adolescent depression; escitalopram and duloxetine are approved for generalized anxiety from age 7. [41][42][43] All antidepressants carry a boxed warning: in pooled pediatric trials, about 4 in 100 had suicidal thoughts or behaviors versus 2 in 100 on placebo, with no suicide deaths in those trials — and benefit-risk analyses favor treatment for most, with close early follow-up. [44][45] Watch for agitation, sleep change, unusual energy, or worsening mood; never stop or adjust without the prescriber.
  • For self-harm and intense emotion swings: dialectical behavior therapy (DBT) adapted for adolescents reduced self-harm in randomized trials — worth seeking out when self-harm is present. [46]
  • School and lifestyle: accommodations that support return rather than cement avoidance; protected sleep; physical activity, which meaningfully reduced symptoms in adolescent trials; substance treatment integrated, not postponed. [47]
  • At 17–18, plan the handoff: adult providers, prescription continuity, college counseling, releases your teen agrees to — before the birthday. [23]

Where to get help

Start with your pediatrician or family clinician for evaluation and referrals. School counselors can support and connect. Your insurer’s directory and community mental health centers list adolescent therapists — many offer telehealth, which some teens prefer. For crisis guidance any hour, call or text 988.

What not to assume

  • That good grades, sports, or jokes rule out depression. Concealment is a teen skill. [15]
  • That talk of death is manipulation, or that asking about suicide plants the idea. Neither is true. [4]
  • That self-harm equals a suicide attempt — or that it can be ignored. Both need assessment. [48]
  • That being LGBTQ+ is the problem. Rejection and mistreatment are the risk factors; acceptance protects. [18][19]
  • That it’s too late. Treatment works at every severity level, and most teens recover.

Takeaways

  1. About 15% of adolescents had a major depressive episode in 2025, and it’s under-treated. Don’t wait for it to announce itself politely. [1]
  2. Irritability, numbness, and quitting loved activities are core signals; so are broken (not just late) sleep and self-care decline. [7][12]
  3. Privacy is development; disappearance is a flag. Track change from your teen’s baseline — high-functioning does not mean healthy. [15]
  4. Burden talk, means-seeking, giving away possessions, goodbye messages, and sudden calm after despair are same-day signals: 988, clinician, or the ER. [9][10]
  5. Ask about suicide in plain words — it doesn’t increase risk. Then secure firearms and medications; means access is where families hold real protective power. [4][5]
  6. Therapy and medication both work; combined treatment works best for moderate-to-severe depression, with close early follow-up. [39][44][45]
  7. Connection protects: warmth, acceptance, and one reliable adult lower risk. [19]

FAQ

How do I ask about suicide without making it worse? Directly and calmly: “Sometimes when people feel this bad, they think about killing themselves. Have you?” Asking does not create risk — silence is the dangerous option. [4]

What if my teen refuses help? Keep the relationship first. Offer choices — a different clinician, telehealth, a trial period — and enlist a trusted adult. “A checkup” lands better than “therapy.” Imminent danger overrides refusal.

What stays private in treatment — and what happens at 18? Clinicians explain their rules up front: therapy content is generally private; safety risks are shared. At 18, your teen controls their own health information — build consent habits now, and ask for the releases they’re comfortable with before adult care. [23]


This article is for education only and is not medical advice, a diagnosis, or a substitute for evaluation by a qualified clinician. Evidence reviewed through August 6, 2026. If your teen may be in danger, call or text 988, or call 911. — Fady Boules, PMHNP-BC

References

  1. Substance Abuse and Mental Health Services Administration. Highlights for the 2025 National Survey on Drug Use and Health. July 2026. https://www.samhsa.gov/data/sites/default/files/NSDUH-2025-Annual-Release/2025-nsduh-nnr-highlights.pdf
  2. Verlenden JV, Fodeman A, Wilkins N, et al. Mental health and suicide risk among high school students and protective factors — Youth Risk Behavior Survey, United States, 2023. MMWR Suppl. 2024;73(4). https://www.cdc.gov/mmwr/volumes/73/su/pdfs/su7304a9-H.pdf
  3. Merikangas KR, He JP, Burstein M, et al. Lifetime prevalence of mental disorders in U.S. adolescents: results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A). J Am Acad Child Adolesc Psychiatry. 2010;49(10):980-989.
  4. Dazzi T, Gribble R, Wessely S, Fear NT. Does asking about suicide and related behaviours induce suicidal ideation? What is the evidence? Psychol Med. 2014;44(16):3361-3363.
  5. Anglemyer A, Horvath T, Rutherford G. The accessibility of firearms and risk for suicide and homicide victimization among household members: a systematic review and meta-analysis. Ann Intern Med. 2014;160(2):101-110.
  6. Lee LK, Fleegler EW, Goyal MK, et al; American Academy of Pediatrics. Firearm-related injuries and deaths in children and youth: injury prevention and harm reduction. Pediatrics. 2022;150(6):e2022060070.
  7. Walter HJ, Abright AR, Bukstein OG, et al. Clinical practice guideline for the assessment and treatment of children and adolescents with major and persistent depressive disorders. J Am Acad Child Adolesc Psychiatry. 2023;62(5):479-502.
  8. Vidal-Ribas P, Brotman MA, Valdivieso I, Leibenluft E, Stringaris A. The status of irritability in psychiatry: a conceptual and quantitative review. J Am Acad Child Adolesc Psychiatry. 2016;55(7):556-570.
  9. 988 Suicide & Crisis Lifeline. Suicide warning signs. https://988lifeline.org/we-can-all-prevent-suicide/warning-signs/ (accessed August 6, 2026)
  10. American Foundation for Suicide Prevention. Risk factors, protective factors, and warning signs. https://afsp.org/risk-factors-protective-factors-and-warning-signs/ (accessed August 6, 2026)
  11. Adolescent Sleep Working Group, Committee on Adolescence, Council on School Health; American Academy of Pediatrics. School start times for adolescents. Pediatrics. 2014;134(3):642-649.
  12. Lovato N, Gradisar M. A meta-analysis and model of the relationship between sleep and depression in adolescents. Sleep Med Rev. 2014;18(6):521-529.
  13. Walter HJ, Bukstein OG, Abright AR, et al. Clinical practice guideline for the assessment and treatment of children and adolescents with anxiety disorders. J Am Acad Child Adolesc Psychiatry. 2020;59(10):1107-1124.
  14. Kearney CA. School absenteeism and school refusal behavior in youth: a contemporary review. Clin Psychol Rev. 2008;28(3):451-471.
  15. De Los Reyes A, Augenstein TM, Wang M, et al. The validity of the multi-informant approach to assessing child and adolescent mental health. Psychol Bull. 2015;141(4):858-900.
  16. Gobbi G, Atkin T, Zytynski T, et al. Association of cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: a systematic review and meta-analysis. JAMA Psychiatry. 2019;76(4):426-434.
  17. The Trevor Project. 2025 U.S. National Survey on the Mental Health of LGBTQ+ Young People. Released May 2026. https://www.thetrevorproject.org/survey-2025/
  18. The Trevor Project. Facts about LGBTQ+ youth suicide. https://www.thetrevorproject.org/resources/article/facts-about-lgbtq-youth-suicide/ (accessed August 6, 2026)
  19. Ryan C, Russell ST, Huebner D, Diaz R, Sanchez J. Family acceptance in adolescence and the health of LGBT young adults. J Child Adolesc Psychiatr Nurs. 2010;23(4):205-213.
  20. Lindsey MA, Sheftall AH, Xiao Y, Joe S. Trends of suicidal behaviors among high school students in the United States: 1991–2017. Pediatrics. 2019;144(5):e20191187.
  21. Congressional Black Caucus Emergency Taskforce on Black Youth Suicide and Mental Health. Ring the alarm: the crisis of Black youth suicide in America. December 2019. https://theactionalliance.org/sites/default/files/ring_the_alarm-_the_crisis_of_black_youth_suicide_in_america_copy.pdf
  22. Benarous X, Consoli A, Raffin M, et al. Catatonia in children and adolescents: new perspectives. Schizophr Res. 2018;200:56-67.
  23. U.S. Department of Health & Human Services. Personal representatives and minors under HIPAA (guidance). https://www.hhs.gov/hipaa/for-professionals/privacy/guidance/personal-representatives/index.html (accessed August 6, 2026)
  24. Angold A, Costello EJ, Erkanli A. Comorbidity. J Child Psychol Psychiatry. 1999;40(1):57-87.
  25. Garber J, Weersing VR. Comorbidity of anxiety and depression in youth: implications for treatment and prevention. Clin Psychol (New York). 2010;17(4):293-306.
  26. Pine DS, Cohen P, Gurley D, Brook J, Ma Y. The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders. Arch Gen Psychiatry. 1998;55(1):56-64.
  27. U.S. Food & Drug Administration. FDA requires boxed warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair). March 4, 2020. https://www.fda.gov/drugs/drug-safety-communications/fda-requires-boxed-warning-about-serious-mental-health-side-effects-asthma-and-allergy-drug
  28. Huang YC, Cheng YC. Isotretinoin treatment for acne and risk of depression: a systematic review and meta-analysis. J Am Acad Dermatol. 2017;76(6):1068-1076.e9.
  29. Stanley B, Brown GK. Safety Planning Intervention: a brief intervention to mitigate suicide risk. Cogn Behav Pract. 2012;19(2):256-264.
  30. Stanley B, Brown GK, Brenner LA, et al. Comparison of the Safety Planning Intervention with follow-up vs usual care of suicidal patients treated in the emergency department. JAMA Psychiatry. 2018;75(9):894-900.
  31. Committee on Practice and Ambulatory Medicine; American Academy of Pediatrics. 2025 recommendations for preventive pediatric health care (periodicity schedule). Pediatrics. 2025;155(5):e2025071066.
  32. US Preventive Services Task Force. Screening for depression and suicide risk in children and adolescents: recommendation statement. JAMA. 2022;328(15):1534-1542.
  33. US Preventive Services Task Force. Screening for anxiety in children and adolescents: recommendation statement. JAMA. 2022;328(14):1438-1444.
  34. Johnson JG, Harris ES, Spitzer RL, Williams JBW. The Patient Health Questionnaire for Adolescents: validation of an instrument for the assessment of mental disorders among adolescent primary care patients. J Adolesc Health. 2002;30(3):196-204.
  35. Horowitz LM, Bridge JA, Teach SJ, et al. Ask Suicide-Screening Questions (ASQ): a brief instrument for the pediatric emergency department. Arch Pediatr Adolesc Med. 2012;166(12):1170-1176.
  36. Zhou X, Hetrick SE, Cuijpers P, et al. Comparative efficacy and acceptability of psychotherapies for depression in children and adolescents: a systematic review and network meta-analysis. World Psychiatry. 2015;14(2):207-222.
  37. Mufson L, Dorta KP, Wickramaratne P, Nomura Y, Olfson M, Weissman MM. A randomized effectiveness trial of interpersonal psychotherapy for depressed adolescents. Arch Gen Psychiatry. 2004;61(6):577-584.
  38. James AC, Reardon T, Soler A, James G, Creswell C. Cognitive behavioural therapy for anxiety disorders in children and adolescents. Cochrane Database Syst Rev. 2020;(11):CD013162.
  39. March J, Silva S, Petrycki S, et al; Treatment for Adolescents With Depression Study (TADS) Team. Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression. JAMA. 2004;292(7):807-820.
  40. Brent D, Emslie G, Clarke G, et al. Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial. JAMA. 2008;299(8):901-913.
  41. Prozac (fluoxetine) prescribing information (pediatric MDD age 8+). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018936s108lbl.pdf
  42. Lexapro (escitalopram) prescribing information, revised May 2023 (MDD age 12+; GAD age 7+). https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/021323s055,021365s039lbl.pdf
  43. Cymbalta (duloxetine) prescribing information (pediatric GAD age 7+). https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021427s052lbl.pdf
  44. U.S. Food & Drug Administration. Suicidality in children and adolescents being treated with antidepressant medications (2004 public health advisory; since removed from fda.gov). Archived copy: https://web.archive.org/web/20260517093045/https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/suicidality-children-and-adolescents-being-treated-antidepressant-medications (accessed August 6, 2026)
  45. Bridge JA, Iyengar S, Salary CB, et al. Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials. JAMA. 2007;297(15):1683-1696.
  46. McCauley E, Berk MS, Asarnow JR, et al. Efficacy of dialectical behavior therapy for adolescents at high risk for suicide: a randomized clinical trial. JAMA Psychiatry. 2018;75(8):777-785.
  47. Recchia F, Bernal JDK, Fong DY, et al. Physical activity interventions to alleviate depressive symptoms in children and adolescents: a systematic review and meta-analysis. JAMA Pediatr. 2023;177(2):132-140.
  48. Swannell SV, Martin GE, Page A, Hasking P, St John NJ. Prevalence of nonsuicidal self-injury in nonclinical samples: systematic review, meta-analysis and meta-regression. Suicide Life Threat Behav. 2014;44(3):273-303.

If you or someone you know is in crisis

  • Call 911 or go to your nearest emergency room for any life-threatening emergency.
  • 988 Suicide & Crisis Lifeline — call or text 988, available 24/7. En español: marque 988 y oprima 2. Veterans: 988 and press 1, or text 838255.
  • Crisis Text Line — text HOME to 741741.
  • The Trevor Project (crisis support for LGBTQ+ young people) — call 1-866-488-7386, or text START to 678-678.
  • National Sexual Assault Hotline (RAINN) — call 1-800-656-HOPE (4673) or text HOPE to 64673; free, confidential, 24/7. Online chat at RAINN.org/hotline.
  • National Domestic Violence Hotline — call 1-800-799-SAFE (7233) or text START to 88788; 24/7, help in 200+ languages. Online chat at TheHotline.org. If your phone or computer may be monitored, calling from a safer device is an option.
  • Riverside CountyInland SoCal Crisis Helpline 951-686-HELP (4357), 24/7 (Inland SoCal United Way / 211+, in partnership with RUHS-BH); Community Access, Referral, Evaluation and Support (CARES) Line 800-499-3008, 24/7.
  • San Bernardino CountyAccess Unit (Behavioral Health Helpline) 888-743-1478, 24/7; Mobile Crisis/CCRT 800-398-0018 (24/7, all ages) or text 909-420-0560. Arrowhead Regional Medical Center (ARMC) has a dedicated walk-in adolescent psychiatric ER (ages 13–17).
  • Children under 13 — call 911 for immediate danger, contact your county's mobile crisis team (they respond to all ages), or go to the nearest pediatric emergency room.
  • California Peer-Run Warm Line (non-crisis — someone to talk to) — call or text 1-855-600-WARM (9276); daytime and evening hours, not a 24/7 line.
  • NP Fady (non-emergency) — for routine scheduling or questions, call (909) 707-6261. This line is not monitored for emergencies.